Clinical Study: Sérivance (1% peauforia FGF + 1% peauvita EGF) vs Retinol
For years, retinol has been the gold standard in anti-aging skincare. But for many, that standard comes at a cost: irritation, peeling, redness, and months of waiting for modest improvements.
A new independent clinical study conducted by Abich S.r.l., a certified ISO 9001 and ISO 13485 testing lab in Italy, compared a 0.3% retinol cream (the highest legal dose for non-prescription skincare) to a novel formula containing 1% Peauvita™ (EGF) and 1% Peauforia™ (FGF-2)—the exact actives used in Sérivance.
The results speak for themselves: the growth factor-based formula delivered superior anti-aging results across nearly every clinical parameter—without any side effects.
“The formula containing growth factors (Sample A) showed statistically significant improvements in firmness, smoothness, barrier repair, and wrinkle reduction—without adverse reactions.”
— Clinical Report, Abich S.r.l.
The clinical results after 30 days
The double-arm study measured 60 women over 30 days using instrumental dermatological assessments. The Sérivance formula outperformed retinol on nearly every measurable sign of skin aging:
• Wrinkle depth decreased by 25.5% with Sérivance. Retinol achieved only 16.3%.
• Wrinkle length dropped by 27.2% vs. 22.2% for retinol.
• Barrier repair (TEWL) improved by 30.7%, a sign of a restored and protected skin barrier—compared to 23.9% for retinol.
• Skin firmness improved by 23.3%, equivalent to retinol but without the irritation.
• Skin smoothness increased by 100% with Sérivance. The retinol group saw just 16.6%.
• No redness, peeling, or dryness was reported in the Sérivance group.
Statistical significance
Wrinkle depth
Wrinkle length
Barrier
Skin firmness
Skin smoothness
Absence of Redness
Absence of Peeling
Sérivance
Retinol Serum
The mechanism: why Sérivance works better.
Retinol works by damaging the upper layers of the skin to force regeneration through inflammation. It stimulates cell turnover by stressing the skin—and this often results in dryness, peeling, and weakened barrier function.
Sérivance works through biological restoration. Its two key ingredients—Peauvita™ (EGF) and Peauforia™ (FGF-2)—are human-identical growth factors that naturally existed in your skin in youth. These actives signal skin cells to renew, rebuild collagen, improve firmness, and restore hydration from within.
Unlike conventional growth factors, the ones in Sérivance are fused to natural plant-derived oleosomes. This patented delivery system:
Mimics the skin’s lipid structure
Penetrates 11.5x deeper than standard formulations
Maintains full activity at room temperature (2-year shelf stability)
Avoids degradation and loss of efficacy—common problems with free-form EGF or FGF.
The result: high performance without irritation, and skin that looks younger—not stressed.
Powered by recombinant biotech actives.
Sérivance is formulated with pharmaceutical-grade recombinant growth factors, made using biotech processes inspired by regenerative medicine and dermatological science.
• 1% Peauvita™ (EGF) – Epidermal Growth Factor for renewal, texture improvement, and brightness.
• 1% Peauforia™ (FGF-2) – Fibroblast Growth Factor for firming, wrinkle reduction, and dermal density.
Both are produced under GMP-grade quality standards, stabilized with plant oleosome fusion, and clinically validated for efficacy and safety.
The future of anti-aging isn’t harsh. it’s intelligent.
Retinol was a breakthrough in its time. But it relies on irritation, inflammation, and long wait times. Sérivance reflects the next generation: gentle, regenerative, and biologically intelligent.
Backed by science. Trusted by dermatologists. Clinically proven in independent trials. Sérivance doesn’t just promise—it delivers.
22,000+ Skin transformations
Unfiltered words from women who see real results.
“This is the only product that actually made a difference.”
Linda T.
“In 2 weeks, I looked fresher and younger.”
Karen M.
“Finally, something that works without irritation.”
Debbie C.
“My skin feels tighter, smoother, and more radiant every morning.”
Jessica L.
Try it risk-free and experience visibly younger skin in just 14 days.
We are so confident in our breakthrough technology that we offer a complete satisfaction guarantee. If you don't see visible improvement in your skin, simply return the bottles (even if empty) for a full refund.
Frequently Asked Questions
How is Sérivance different from other anti-aging products?
While most products target secondary symptoms, Sérivance addresses the primary root cause: Growth Factor Decline. By stopping this first domino in the aging cascade, we create comprehensive rejuvenation rather than temporary cosmetic effects.
How quickly will I see results from restoring growth factors?
Most users notice initial improvements within 14 days, with significant transformation by 30 days. Because we're restoring fundamental cellular communication, results continue to improve through 90 days as new, properly functioning cells reach the surface.
Is addressing Growth Factor Decline safe for sensitive skin?
Yes! Our formula uses biomimetic growth factors that are recognized by your skin as natural, mimicking the same signals your body produced abundantly in youth. The serum is free from harsh irritants, making it suitable for all skin types.
Can I use Sérivance with my current skincare?
Absolutely. While Sérivance delivers comprehensive benefits by addressing the primary mechanism of aging, it works well with other products. Apply it first to clean skin to ensure maximum penetration, then follow with your usual routine.
Why do I need a 3-month supply to address Growth Factor Decline?
Your skin's complete cellular regeneration cycle takes approximately 90 days. The 3-month protocol ensures continuous support throughout this entire process, allowing for maximum transformation as cellular communication fully restores.
"... in less than 1 week"
Try it risk-free and experience visibly younger skin in just 14 days.
We are so confident in our breakthrough technology that we offer a complete satisfaction guarantee. If you don't see visible improvement in your skin, simply return the bottles (even if empty) for a full refund.